Convinced that the Communists are polluting the American nation, a general orders, in a fit of madness, a surprise nuclear air strike on the Soviet Union. His assistant, Captain Mandrake, tries to figure out the code to stop the bombing.
To solve the problem, the president of EE. UU. communicates with Moscow to convince the Soviet leader that the attack is a stupid mistake. Meanwhile, the president's advisor, a former Nazi scientist, Dr. Strangelove, confirms the existence of the "Doomsday Machine", a Soviet retaliatory device capable of wiping out humanity forever.